Side Effects poster
Where to stream

Side Effects

6.620131h 46mRMovieThrillerCrimeDrama

A woman turns to prescription medication as a way of handling her anxiety concerning her husband's upcoming release from prison.

DirectorSteven Soderbergh
WriterScott Z. Burns
ProducersLorenzo di Bonaventura·Gregory Jacobs

Where to watch

Amazon Prime VideoAmazon Prime VideoAmazon Prime Video with AdsAmazon Prime Video with AdsShout! Factory Amazon ChannelShout! Factory Amazon ChannelKanopyKanopyThe Roku ChannelThe Roku ChannelPluto TVPluto TVShout! Factory TVShout! Factory TVYouTube FreeYouTube FreePlexPlexPlex ChannelPlex ChannelTubi TVTubi TV
Availability shown for United States · rights vary by country

Cast · Directed by Steven Soderbergh

RMRooney Mara
Rooney Mara
Emily Taylor
JLJude Law
Jude Law
Jonathan Banks
CZCatherine Zeta-Jones
Catherine Zeta-Jones
Dr. Victoria Siebert
CTChanning Tatum
Channing Tatum
Martin Taylor
VSVinessa Shaw
Vinessa Shaw
Dierdre Banks
ADAnn Dowd
Ann Dowd
Mrs. Taylor
PDPolly Draper
Polly Draper
Eileen Spicer
DCDavid Costabile
David Costabile
Carl
MGMamie Gummer
Mamie Gummer
Kayla
SSScott Shepherd
Scott Shepherd
NYPD Detective
MIMarin Ireland
Marin Ireland
Upset Visitor
ERElizabeth Rodriguez
Elizabeth Rodriguez
Pharmacist

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More from Steven Soderbergh · Director

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Side Effects — streaming FAQ

Which OTT platform streams Side Effects?

Side Effects is streaming on Amazon Prime Video, Shout! Factory and Kanopy in United States, and available to rent or buy on Amazon Video and Apple TV Store. It's not currently on Netflix.

Is Side Effects on Netflix?

No, Side Effects is not on Netflix in United States as of September 2026. It's currently on Amazon Prime Video and Shout! Factory.

Is Side Effects on Amazon Prime Video?

Yes — Side Effects is included with an Amazon Prime Video subscription in United States as of September 2026.

Where can I watch Side Effects for free?

Side Effects is available to stream free (with ads) on Kanopy and The Roku Channel in United States.