Painkiller Jane poster
Where to stream

Painkiller Jane

6.020071 seasonTV-MATV SeriesSci-Fi & FantasyAction & Adventure

Painkiller Jane is an American-Canadian science fiction and action television series based on the comic book character of the same name. Airing on the Sci Fi Channel in the US starting April 13, 2007 and Global in Canada, it starred…

ProducersKristanna Loken·Lawrence Hertzog

Where to watch

The CWThe CW
Availability shown for United States · rights vary by country

Seasons & Episodes

E1
Pilot
Apr 13, 2007
E2
Toy Soldiers
Apr 20, 2007
E3
Piece of Mind
Apr 27, 2007
E4
Catch Me if You Can
May 4, 2007
E5
Nothing To Fear But Fear Itself
May 11, 2007
E6
Breakdown
May 18, 2007
E7
Higher Court
Jun 1, 2007
E8
Friendly Fire
Jun 8, 2007
E9
Trial by Fire
Jun 15, 2007
E10
Portraits of Lauren Gray
Jun 22, 2007
E11
Ghost in the Machine
Jun 29, 2007
E12
Something Nasty in the Neighborhood
Jul 6, 2007
E13
The League
Jul 13, 2007
E14
The Amazing Howie
Jul 20, 2007
E15
The Healer
Jul 27, 2007
E16
Thanks For the Memories
Aug 3, 2007
E17
Playback
Aug 17, 2007
E18
Jane 113
Aug 24, 2007
E19
What Lies Beneath
Aug 31, 2007
E20
The Beast of Bolnar
Sep 7, 2007
E21
Reflections
Sep 14, 2007 5.0
E22
Endgame
Sep 21, 2007

Cast

Kristanna Loken
Kristanna Loken
Jane Vasco
Rob Stewart
Rob Stewart
Andre McBride
Noah Dalton Danby
Noah Dalton Danby
Connor King
Stephen Lobo
Stephen Lobo
Seth Carpenter
Sean Owen Roberts
Sean Owen Roberts
Riley Jensen

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Painkiller Jane — streaming FAQ

Which OTT platform streams Painkiller Jane?

Painkiller Jane is streaming on The CW in United States, and available to rent or buy on Amazon Video and Apple TV Store. It's not currently on Netflix.

Is Painkiller Jane on Netflix?

No, Painkiller Jane is not on Netflix in United States as of August 2026. It's currently on The CW.

Is Painkiller Jane on Amazon Prime Video?

Painkiller Jane isn't included with a Prime Video subscription in United States, but you can rent or buy it on Amazon Video.

Where can I watch Painkiller Jane for free?

Painkiller Jane is available to stream free (with ads) on The CW and The Roku Channel in United States.

How many seasons are in Painkiller Jane?

Painkiller Jane has 1 season in total (22 episodes). The series concluded in 2007.

Are all episodes of Painkiller Jane out yet?

Yes — all 22 episodes across 1 season of Painkiller Jane are out and available to stream.

Is there a Season 2 of Painkiller Jane?

No — Painkiller Jane ended after 1 season, so there is no Season 2.

What comic is Painkiller Jane based on?

Painkiller Jane is based on Painkiller Jane.